29, January 2025

Transforming Hope into Healing: The Role of Nursing in Bone Marrow Transplant for Acute Myelogenous Leukemia

Author(s): 1. Alphonsa George, 2. Pradeepha N., 3. Subbha Rao Suma Kannakatte,

Authors Affiliations: 1.Clinical Nurse Lead Specialist, Apollo hospitals, BG Road, Bangalore. 2.Clinical Nurse Lead Specialist, Apollo hospitals, BG Road, Bangalore. 3.General Manager-Nursing, Apollo hospitals, BG Road, Bangalore.

DOIs:10.2019/JSHE/202501001     |     Paper ID: JSHE202501001


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This case study examines the management and clinical outcomes of a 25-year-old male who have been diagnosed with acute myelogenous leukemia (AML), a rapidly progressing hematologic malignancy. Despite undergoing multiple rounds of chemotherapy, the patient failed to achieve remission, necessitating an allogeneic bone marrow transplant (BMT) from a fully HLA-matched sibling donor. The pre-transplant conditioning regimen involved high-dose chemotherapy, followed by stem cell infusion. The patient was carefully monitored for common post-transplant complications, includes infection, graft-versus-host disease (GVHD), and mucositis. Following a successful engraftment phase and supportive care, the patient showed good outcomes, with improved blood counts and stable recovery. Nursing care was central throughout the process, with key responsibilities including infection prevention, pain management, nutritional support, and monitoring for complications such as graft-versus-host disease (GVHD) and mucositis. Nurses played a vital role in implementing strict infection control protocols, providing education on self-care and signs of complications, and supporting the patient emotionally during the transplant process. In Post-transplant care we monitored blood counts, and took precautions in order to prevent infections, and side effects of chemotherapy were addressed. The successful outcome of this case highlights the importance of comprehensive nursing interventions in improving patient recovery, minimizing complications, and ensuring a smoother recovery process post-BMT.

Bone marrow transplantation, acute myelogenous leukemia, nursing care.

Alphonsa George,  Pradeepha N,  Subbha Rao Suma Kannakatte (2025);  Transforming Hope into Healing: The Role of Nursing in Bone Marrow Transplant for Acute Myelogenous Leukemia,  Journal of Science and Healthcare Exploration (JSHE), Vol-7, Issue-1, Pp.1-6.   Available on – https://jshe.researchculturesociety.org/

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